Review Confirms Reduced Seriousness of Omicron SARS-CoV-2 Variant of Concern

In a recent study, researchers review existing literature to quantify the transmissibility, immune evasion, reinfection, and severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant.

As a result of its high transmissibility, the SARS-CoV-2 Omicron variant is rapidly spreading across the world. In the United States, for example, this strain of SARS-CoV-2 is responsible for 95% of all new coronavirus disease 2019 (COVID-19) cases since January 1, 2022.

Extensive research is needed to understand the extent to which the increased transmissibility and virulence of Omicron threaten public health globally. Furthermore, it is also crucial to determine how the global population should recognize these dynamics, perceive risk, and adhere to public health and social measures amid the emergence of the Omicron variant.

Study

In the present study, the researchers performed a literature search in PubMed, Web of Science, Scopus, ScienceDirect, Google Scholar, medRxiv, and bioRxiv using keywords such as Omicron, transmissibility, immune evasion, reinfection, and severity to find articles published in 2021 and 2022. Data reviewed in the present study included all the existing articles having at least one of these keywords.

Almost all the studies reviewed in the current work consistently showed that the severity of infection in Omicron cases is much lower compared to Delta and other previous variants. Subsequently, there is a considerably lower risk of requiring hospital admission, intensive care unit (ICU) admission, and mechanical ventilators in Omicron-infected individuals. Furthermore, Omicron infections were associated with shorter hospital stays and lower mortality rates. Although Omicron has an enhanced ability to escape immunity developed by vaccines, booster doses significantly protect individuals from symptomatic COVID-19 infections.

Therefore, the authors strongly recommend the continuance of usual prevention measures, such as vaccination, masking, and suitable infection mitigation strategies for decreasing Omicron transmission, reducing morbidity and death to ultimately reduce the workload of healthcare systems globally.

Full details: https://www.tridhascholars.org/press-release/review-confirms-reduced-seriousness-of-omicron-sars-cov-2-variant-of-concern.php




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