New Omicron Subvariant BA.2

Omicron has approximately 60 mutations, it is thought that its sister lineage may have 85 mutations. The World Health Organization (WHO) stated over the weekend that this lineage differs from the original Omicron strain by several mutations, including those of the spike protein, the SARS-CoV-2 protein that mediates host cell entry. This variant has also been termed the “stealth variant” due to a mutation that renders it ‘invisible’ as Omicron to PCR testing.

BA.2 has spread to over 40 countries, including the US, UK, India, Australia, and Norway. In the latter, it currently accounts for half of Omicron cases. It is currently unknown why BA.2 has dominated so quickly in Norway; however, enhanced immune escape or transmissibility has been suggested.

Current reports liken the symptoms of the new lineage to that of the original strain of Omicron: sore throat, headaches, nausea, etc. It is believed that there are no differences in disease severity, with some even suggesting the symptoms are milder.

Scientists currently understand that previous Omicron infection confers protection against BA.2 and expect the already developed vaccines to be effective against the Omicron subvariant. Nonetheless, the WHO has made recommendations that understanding the immune escape characteristics of BA.2 is of great priority.

With reports of yet another Omicron subvariant, BA.3, it is of ever-increasing importance to track the emergence of new SARS-CoV-2 strains and understand their implications on public health.


Reference: https://www.tridhascholars.org/press-release/as-per-the-study-what-we-know-so-far-about-new-omicron-subvariant-ba-2.php




Comments

Post a Comment

Popular posts from this blog

COVID- 19 Observation for Fully Vaccinated and Boosted Patients

The researchers concluded that booster doses provided protection against severe COVID-19 symptoms and also observed that the number of patients requiring   mechanical ventilation   and use of vasopressors, as well as in-hospital mortality, were lower in the FV&B cohorts as compared to the UV cohorts, despite a higher risk for in-hospital mortality in the FV&B cohort. When the researchers compared the FV&B patients who required ICU care to those who did not, it was observed that there may not have been enough time for the booster dose in these patients to be effective in preventing COVID-19 symptoms. Decreased in-hospital mortality was observed in FV&B patients compared to UV patients, even though the former group was older and had a higher rate of pre-existing ESRD, higher proportion of immunocompromised state, and a higher proportion of immunocompromised state risk of in-hospital death in the FV&B cohort. It was observed that even among elderly patients with signi
Read more

SARS-CoV-2 Infection and Nasopharyngeal Microbiota

C anadian researchers investigated how  severe acute respiratory syndrome coronavirus 2  (SARS-CoV-2) infection altered the microbiota composition of the host’s nasopharyngeal region. The risk and clinical outcomes of SARS-CoV-2 infection vary widely among individuals. However, the mechanisms underlying these differences in  coronavirus disease 2019  (COVID-19) progression and pathogenesis remain unclear. Studies have shown that the mucosal microbiome influences host toll-like receptor (TLR) expression, which is involved in virus detection. Studies have also shown the prevalence of bacterial co-infections in COVID-19 patients at 6.9%. Likewise, elevated nasal cytokines have been implicated in adverse clinical outcomes in influenza patients. Therefore, exploring upper respiratory tract microbiota compositional changes following SARS-CoV-2 infection could help evaluate its impact on  infection  severity. Overall, the study results presented a granular picture of the microbiota difference
Read more

TRIDHA Scholars : An Open Access Publisher

 HI... TRIDHA Scholars is an open access Publishing company of India and it publishes all kind of paper related to clinical and medical field of Science. We have around 10 running journals on the very kind of particular topic of Clinical Science. Here is the list of the journals below. 1. Journal of Clinical Cases and Report 2. International Journal of Clinical and Medical Informatics 3. Clinical Surgery Journal 4. Cancer Medicine Journal 5. Journal of Medicine and Biology 6. Clinical Practice and Investigation 7. Journal of Heart 8. Case Reports in Dental Science 9. Food Processing and Nutrional Science 10. International Journal of AAYUSH and Traditional Medicine (Official Journal of  SGM, Ayurveda Mahavidyalaya, Pusad, Pune, India ) So, we would like to share it and help us to contribute in scientific community by publishing their work on time. We assure the quality process and complete the peer review process without any fail. Web: https://www.tridhascholars.org/ Contact: contact.tr
Read more